“LOVE AT FIRST BITE’’

Snake venom can be deadly - but similar substances can also heal!!

Lines caused by facial expressions are always visible. We use about 60 facial muscles whilst communicating both through speech and with facial expressions, frowning, the lifting of eyebrows, laughing and pulling a face are some typical facial expressions that we use to communicate.

As time passes and with frequent use of these facial movements, these wrinkles persist and become permanent deep wrinkles on the forehead, laughter lines and crow’s feet. Those who no longer want to live with these can now spare themselves the danger and discomfort of cosmetic surgery or the use of expensive Botulism Toxin injections.

Syn®-ake solves this problem on a strictly cosmetic basis. The new synthetic Tripeptide mimics the effect of Waglerin-1, which is a protein found in the venom of the Temple Viper (Tropidolaemus wagleri). The viper owes its name to the German herpe- tologist Johann Georg Wagler. At the beginning of the 19th century, he analysed and described it. The Temple~ Viper is found in great numbers in the Snake Temple of the island Penang, Malaysia. It has enjoyed cult status there for the last 150 years. Waglerin-1 Inhibits neuromuscular communication.

Once the snake has bitten its prey the venom blocks the nerve impulses to the muscles, thereby paralysing its victim. Whereas this causes death, the synthetic imitation of parts of the venom only causes relaxation of facial muscle contractions, resulting in a smooth skin and a renewed enjoyment of life.

The effectiveness of this substance is astounding: it has excellent skinsmoothing properties and reduces the depth of facial wrinkles in just a few days. A study involving 45 volunteers confirmed these results. During this test, the use of SYN®-AKE twice daily-reduced forehead wrinkles, by up to 52% in just 28 days.

The in vivo studies dealing with crow’s feet confirmed the efficiency of the product. In vitro studies show that SYN®-AKE, in a concentration of 0.5 mm, reduces the frequency of muscle contractions in innervated muscle cells by 82% (p<O.05) within only 2 hours.

INCI Listing For Label

Water (Aqua), Aloe Barbadensis Leaf Juice, Emulsifying Wax, C12-15 Alkyl Benzoate, Ceteareth 20, Cetyl Esters, Stearic Acid, Dimethicone, Caprylic Capric Triglyceride, Butyrospermum Parkii (Shea Butter) Fruit, Glycerine, Acetyl Hexapeptide-8, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Butylene Glycol, Carbonner, Polysorbate 20, (Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7), Acetyl Hexapeptide-3, hyaluronic Acid, Squalane (Olive), Phenoxyethanol, Caprylyl Glycol, Disodium EDTA, Tocopherol Acetate, Triethanolamine, Potassium Sorbate

Active Ingrediants In The Product

Syn®-Ake is an anti-wrinkle active compound based on a synthetic tripeptide that mimics the effect of Waglerin 1, found in the venom of the Temple Viper. The biological activity of Syn®-Ake reduces the contraction frequency of muscle cells on the face, thereby decreasing expression lines. It prevents the fixation of acetylcholine – the ‘contraction messenger’ for facial muscles that calms the muscle contractions that would increase wrinkling. In vivo testing showed an impressive reduction of over 50% in wrinkle size after 28 days.
INCI Name: Dipeptide Diaminobutyroyl Benzylamide Diacetate

Syn®-Coll is a synthetic peptide designed to stimulate the skin’s natural mechanism to produce collagen. It is based on a small peptide developed to reduce any type of wrinkles. Clinical trials have shown that Syn®-Collis capable of reducing and changing the type and aspect of wrinkles that add years to your appearance.
INCI Name: Palmitoyl Tripeptide-5.

Argireline® NP (Paraben-Free) offers superior anti-wrinkle efficacy. Studies show it reduces the depth of expression wrinkles, especially in the forehead and around the eyes. It is a safer, less expensive and milder alternative to Botulism Toxin, topically targeting the same wrinkleformation mechanism in a very different way. Argireline® NP is believed to function through modulation of the SNARE complex formulation. Recommended concentration
INCI Name: Acetyl Hexapeptide-3. Note that this peptide is claimed to be a good alternative to Botulism Toxin, which is one of its main selling points.

Matrixyl - 3000® is a combination of matrikines including Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide – 7, Matrixyl 3000® promotes collagen production while stimulating fibroblast cells in the skin, enabling them to significantly reduce the appearance of wrinkles. Although fibroblasts never completely lose their ability to create more collagen, the levels dwindle with age and the skin dries out and wrinkles.

In Clinical Trials , Matrixyl® 3000 Achieved:

• 33% decrease in wrinkle density
• 23% decrease in the volume of wrinkles
• 20% decrease in the depth of wrinkles

INCI Name: Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide – 7

Beneficial Ingredients In The Product:

Hyaluronic Acid: has water storing properties and is an ideal swelling agent and lubricant, enabling its incorporation into cosmetics leading to a perceptible and visible improvement of skin condition. It forms a thin transparent pliable surface film. The film helps to preserve the properties of youthful and healthy skin, suppleness, elasticity and tone. The benefits of its humectant and moisturising properties make this a very effective skin care component.

Squalane (Olive derived): Squalane is a major component of human skin surface lipids (or oils). Squalane helps keep our skin soft and healthy and its anti-oxidant capabilities help to protect the skin from the harsh effects of the environment. Although Squalane is often derived from shark liver oil, our Squalane is derived from olives, which is a vegetable source.

Aloe Vera (Aloe Barbaensis Leaf Juice): The benefits of Aloe Vera on the skin have been known for many years and therefore it is an essential ingredient in skin care products.

DMR Labs Ltd is proud to announce that a new product name has been fully trademarked with the Intellectual Property Office for the UK and Europe.

Price:
Introductory Price £24.95 rrp 170ml
Salon Price £12.50 (minimum order of 6)